Obstetrician Mindy Lahiri's love of romantic comedies leads her into trouble when she meets fellow resident Tom and thinks he's The One. But he eventually dumps her for a younger woman and Mindy humiliates herself by making a drunken speech at his wedding. She decides to change the course of her life with mixed results.
- Mindy Kaling as Mindy Lahiri
- Chris Messina as Danny Castellano
- Ed Weeks as Jeremy Reed
- Anna Camp as Gwen Grandy
- Zoe Jarman as Betsy Putch
- Amanda Setton as Shauna Dicanio
- Stephen Tobolowsky as Marc Shulman